abYsis

Numbering & Regions

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Region Sequence Details

Regions Definition:

Region	Sequence Fragment	Residues	Length
HFR1	EVQLVESGGGLVQPGRSLRLSCAASGFTFN	1 - 30	30
CDR-H1	DYAMH	31 - 35	5
HFR2	WVRQAPGKGLEWVS	36 - 49	14
CDR-H2	GISWDSSSIGYADSVKG	50 - 66	17
HFR3	RFTISRDNAKNSLYLQMNSLRAEDMALYYCVK	67 - 98	32
CDR-H3	GRDYYDSGGYFTVAFDI	99 - 115	17
HFR4	WGQGTMVTVSS	116 - 126	11
Tail	ASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSS GLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC	127 - 229	103
			229

Humanness

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Accession & Annotations

Accession	1dfb_H
Source	PDB 1dfb Submitted 27-MAR-1992 Updated 25-AUG-2009
Name	STRUCTURE OF A HUMAN MONOCLONAL ANTIBODY FAB FRAGMENT AGAINST GP41 OF HUMAN IMMUNODEFICIENCY VIRUS TYPE I
Organism	Homo sapiens
Human Subgroup	Heavy chain subgroup III
Chain Type	Heavy
Pairing	1dfb_L
Identical Protein Sequences	None
References	HE M., RUKER F., CASALE E., CARTER C. 'STRUCTURE OF A HUMAN MONOCLONAL ANTIBODY FAB FRAGMENT AGAINST GP41 OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1.' PROC.NATL.ACAD.SCI.USA V. 89 7154 1992 ISSN 0027-8424

Sequences

Amino Acid Sequence:

EVQLVESGGGLVQPGRSLRLSCAASGFTFNDYAMHWVRQAPGKGLEWVSGISWDSSSIGY
ADSVKGRFTISRDNAKNSLYLQMNSLRAEDMALYYCVKGRDYYDSGGYFTVAFDIWGQGT
MVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFP
AVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC

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