abYsis

Numbering & Regions

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Region Sequence Details

Regions Definition:

Region	Sequence Fragment	Residues	Length
LFR1	DIELTQSPLSLPVSLGDQASISC	1 - 23	23
CDR-L1	RSSQSLVHSNGNTSLH	24 - 39	16
LFR2	WYLKKPGQSPKLLIY	40 - 54	15
CDR-L2	KVSTRFS	55 - 61	7
LFR3	GVPDRFSGSGSGTDFTLKISRVEAEDLGVYFC	62 - 93	32
CDR-L3	SQSTHVPFT	94 - 102	9
LFR4	FGSGTKLELK	103 - 112	10
			112

Region	Definition	Sequence Fragment	Residues	Length
LFR1	Chothia	DIELTQSPLSLPVSLGDQASISC------	1 - 23	23
	AbM	DIELTQSPLSLPVSLGDQASISC------	1 - 23	23
	Kabat	DIELTQSPLSLPVSLGDQASISC------	1 - 23	23
	Contact	DIELTQSPLSLPVSLGDQASISCRSSQSL	1 - 29	29
	IMGT	DIELTQSPLSLPVSLGDQASISCRSS---	1 - 26	26
CDR-L1	Chothia	RSSQSLVHSNGNTSLH--	24 - 39	16
	AbM	RSSQSLVHSNGNTSLH--	24 - 39	16
	Kabat	RSSQSLVHSNGNTSLH--	24 - 39	16
	Contact	------VHSNGNTSLHWY	30 - 41	12
	IMGT	---QSLVHSNGNTS----	27 - 37	11
LFR2	Chothia	--WYLKKPGQSPKLLIY	40 - 54	15
	AbM	--WYLKKPGQSPKLLIY	40 - 54	15
	Kabat	--WYLKKPGQSPKLLIY	40 - 54	15
	Contact	----LKKPGQSPK----	42 - 50	9
	IMGT	LHWYLKKPGQSPKLLIY	38 - 54	17
CDR-L2	Chothia	----KVSTRFS	55 - 61	7
	AbM	----KVSTRFS	55 - 61	7
	Kabat	----KVSTRFS	55 - 61	7
	Contact	LLIYKVSTRF-	51 - 60	10
	IMGT	----KV-----	55 - 56	2
LFR3	Chothia	-----GVPDRFSGSGSGTDFTLKISRVEAEDLGVYFC	62 - 93	32
	AbM	-----GVPDRFSGSGSGTDFTLKISRVEAEDLGVYFC	62 - 93	32
	Kabat	-----GVPDRFSGSGSGTDFTLKISRVEAEDLGVYFC	62 - 93	32
	Contact	----SGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFC	61 - 93	33
	IMGT	STRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFC	57 - 93	37
CDR-L3	Chothia	SQSTHVPFT	94 - 102	9
	AbM	SQSTHVPFT	94 - 102	9
	Kabat	SQSTHVPFT	94 - 102	9
	Contact	SQSTHVPF-	94 - 101	8
	IMGT	SQSTHVPFT	94 - 102	9
LFR4	Chothia	-FGSGTKLELK	103 - 112	10
	AbM	-FGSGTKLELK	103 - 112	10
	Kabat	-FGSGTKLELK	103 - 112	10
	Contact	TFGSGTKLELK	102 - 112	11
	IMGT	-FGSGTKLELK	103 - 112	10

Humanness

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Accession & Annotations

Accession	1lmk_E_ii
Source	PDB 1lmk Submitted 29-AUG-1994 Updated 24-FEB-2009
Name	THE STRUCTURE OF A BIVALENT DIABODY
Organism	Mus musculus
Chain Type	Light
Pairing	1lmk_G_i
Identical Protein Sequences	PDB: 1lmk_A_ii 1lmk_C_ii 1lmk_G_ii
References	PERISIC O., WEBB A., HOLLIGER P., WINTER G., WILLIAMS L. 'CRYSTAL STRUCTURE OF A DIABODY, A BIVALENT ANTIBODY FRAGMENT.' STRUCTURE V. 2 1217 1994 ISSN 0969-2126

Sequences

Amino Acid Sequence:

DIELTQSPLSLPVSLGDQASISCRSSQSLVHSNGNTSLHWYLKKPGQSPKLLIYKVSTRF
SGVPDRFSGSGSGTDFTLKISRVEAEDLGVYFCSQSTHVPFTFGSGTKLELK